Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199600 | 0.78 | EGLN1 (0.45) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15733262 | 0.75 | MEN1 (0.56) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL6201569 | 0.72 | KMT2A (0.46) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6199043 | 0.71 | EGLN1 (0.45) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6195322 | 0.69 | EGLN1 (0.44) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6200817 | 0.68 | NR3C1 (0.49) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6692123 | 0.68 | MAPT (0.46) | MEN1KMT2AMAPT | |
| SCHEMBL6288555 | 0.68 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL6698557 | 0.68 | SMN1; SMN2 (0.46) | KMT2AMAPTALDH1A1 | |
| SCHEMBL6201571 | 0.68 | SMN1; SMN2 (0.45) | MEN1KMT2AMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |