Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319605 | 0.87 | LMNA (0.83) | LMNASMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL5318251 | 0.86 | LMNA (0.65) | LMNASMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL8290730 | 0.84 | MEN1 (0.57) | LMNASMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL29742239 | 0.82 | L3MBTL1 (0.77) | LMNASMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL29742293 | 0.82 | L3MBTL1 (0.70) | LMNASMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL27921658 | 0.82 | LMNA (0.59) | LMNASMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL3519346 | 0.81 | LMNA (1.00) | LMNASMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL5520675 | 0.81 | SMN1; SMN2 (0.72) | LMNASMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL8355388 | 0.81 | LMNA (0.78) | LMNASMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL16564108 | 0.80 | PRSS1 (0.50) | LMNASMN1; SMN2L3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506156-A1 | METHOD FOR PREPARING 2-ALKOXYPHENOXYETHANAMINES FROM 2-ALKOXYPHENOXYETHYLACETAMIDES | MCM PHARMA GMBH (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003095416-A1 | METHOD FOR PREPARING 2-ALKOXYPHENOXYETHANAMINES FROM 2-ALKOXYPHENOXYETHYLACETAMIDES | MCM PHARMA GMBH (DE) | 2003-11-20 | — | — | WO | disclosed |