Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631739 | 0.83 | TACR1 (0.41) | TACR1TACR2 | |
| SCHEMBL4631237 | 0.79 | CYP2D6 (0.36) | TACR1 | |
| SCHEMBL6196433 | 0.78 | TACR1 (0.42) | TACR1TACR2 | |
| SCHEMBL6201334 | 0.73 | CCR5 (0.39) | TACR2 | |
| SCHEMBL4630898 | 0.72 | TACR1 (0.44) | TACR1TACR2 | |
| SCHEMBL6196499 | 0.72 | CCR5 (0.39) | TACR2 | |
| SCHEMBL6202591 | 0.70 | TACR2 (0.38) | TACR2 | |
| SCHEMBL6199169 | 0.69 | TACR2 (0.39) | TACR2 | |
| SCHEMBL7750052 | 0.69 | TACR1 (0.40) | TACR1TACR2 | |
| SCHEMBL4631772 | 0.69 | TACR2 (0.47) | TACR1TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048658-B1 | ALICYCLIC ACYLATED HETEROCYCLIC DERIVATIVES | SANKYO CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6288059-B1 | ANTIASTHMATIC, ANTIALLERGEN AGENTS; URINARY INCONTINENCE; NATURAL KILLER CELL RECEPTOR AND TACHYKININ ANTAGONISTS | SANKYO COMPANY, LIMITED (JP) | 2001-09-11 | — | — | US | disclosed |
| CN-1284070-A | Alicyclic acylated heterocyclic derivatives | SANKYO CO (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1048658-A1 | ALICYCLIC ACYLATED HETEROCYCLIC DERIVATIVES | Sankyo Company Limited (JP) | 2000-11-02 | — | — | EP | disclosed |