Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16799873 | 0.82 | MAPT (0.37) | FFAR4FFAR1GPR84LMNA | |
| SCHEMBL6200312 | 0.77 | — | — | |
| SCHEMBL4941600 | 0.75 | GPR84 (0.34) | FFAR1GPR84LMNAKDM4E | |
| SCHEMBL5705327 | 0.75 | MAPT (0.42) | FFAR4FFAR1GPR84ALDH1A1 | |
| SCHEMBL5705372 | 0.75 | MAPT (0.42) | FFAR4FFAR1GPR84ALDH1A1 | |
| SCHEMBL19003499 | 0.74 | DNM1 (0.30) | — | |
| SCHEMBL6216857 | 0.72 | — | — | |
| SCHEMBL6242225 | 0.71 | — | — | |
| SCHEMBL5027006 | 0.71 | FFAR4 (0.50) | FFAR4FFAR1GPR84ALDH1A1NFKB1 | |
| Hydrochloric Acid SCHEMBL8089311 | 0.70 | SLC2A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597223-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004067489-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |