Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132603 | 0.85 | HPGD (0.53) | L3MBTL1MAPTKMT2AMEN1HPGD | |
| SCHEMBL11620182 | 0.83 | LMNA (0.51) | MAPTNPC1RAB9AKMT2AHPGD | |
| SCHEMBL3377072 | 0.82 | L3MBTL1 (0.58) | L3MBTL1MAPTPIK3CANPC1RAB9A | |
| SCHEMBL11146920 | 0.81 | ALDH1A1 (0.45) | L3MBTL1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7663868 | 0.81 | USP2 (0.64) | L3MBTL1MAPTPIK3CANPC1RAB9A | |
| SCHEMBL29351857 | 0.81 | USP2 (0.64) | L3MBTL1MAPTPIK3CANPC1RAB9A | |
| SCHEMBL11296677 | 0.80 | L3MBTL1 (0.56) | L3MBTL1MAPTPIK3CANPC1RAB9A | |
| SCHEMBL8956326 | 0.79 | L3MBTL1 (0.54) | L3MBTL1MAPTPIK3CANPC1RAB9A | |
| SCHEMBL6295186 | 0.79 | USP2 (0.70) | L3MBTL1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL21661969 | 0.79 | ESRRG (0.45) | PIK3CANPC1RAB9AKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |