Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198849 | 0.88 | EGLN1 (0.51) | ALDH1A1LMNAEGLN1CNR2POLA1 | |
| SCHEMBL6198909 | 0.87 | SCN2A (0.51) | ALDH1A1LMNAEGLN1MCL1SCN2A | |
| SCHEMBL6200824 | 0.87 | EGLN1 (0.48) | ALDH1A1LMNAEGLN1POLA1MEN1 | |
| SCHEMBL6198157 | 0.86 | EGLN1 (0.55) | ALDH1A1LMNAEGLN1NSD2CNR2 | |
| SCHEMBL6194761 | 0.85 | POLA1 (0.54) | ALDH1A1LMNAEGLN1CNR2POLA1 | |
| SCHEMBL6202819 | 0.85 | L3MBTL1 (0.46) | ALDH1A1LMNAEGLN1MCL1SCN2A | |
| SCHEMBL6225327 | 0.85 | MMP13 (0.49) | ALDH1A1EGLN1MCL1POLA1NR3C1 | |
| SCHEMBL6200817 | 0.84 | NR3C1 (0.49) | LMNAEGLN1POLA1MEN1KMT2A | |
| SCHEMBL6198072 | 0.84 | EGLN1 (0.47) | ALDH1A1LMNAEGLN1CNR2POLA1 | |
| SCHEMBL6200449 | 0.84 | PTGER4 (0.48) | ALDH1A1LMNAEGLN1CNR2POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | disclosed |