Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1832768 | 0.85 | L3MBTL1 (0.72) | L3MBTL1MAPK1KMT2AMEN1POLB | |
| SCHEMBL3343714 | 0.85 | ALDH1A1 (0.70) | MAPK1KMT2APOLBNPC1LMNA | |
| SCHEMBL12793245 | 0.84 | POLB (0.88) | L3MBTL1MAPK1KMT2AMEN1POLB | |
| SCHEMBL334552 | 0.84 | ALDH1A1 (0.73) | L3MBTL1MAPK1KMT2AMEN1POLB | |
| SCHEMBL2744785 | 0.84 | L3MBTL1 (0.70) | L3MBTL1MAPK1KMT2AMEN1POLB | |
| SCHEMBL22076808 | 0.83 | USP2 (0.69) | L3MBTL1MAPK1KMT2APOLBNPC1 | |
| SCHEMBL15773014 | 0.82 | TSHR (0.73) | MAPK1KMT2AMEN1NPC1GAA | |
| SCHEMBL28072234 | 0.81 | POLB (0.76) | L3MBTL1MAPK1KMT2AMEN1POLB | |
| SCHEMBL4709068 | 0.81 | LMNA (0.74) | L3MBTL1KMT2AMEN1POLBNPC1 | |
| SCHEMBL12793846 | 0.80 | KMT2A (0.72) | L3MBTL1MAPK1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |