Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 6/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | TLR2 | O60603 | 2/20 | 0.68 |
| ▸ | CNR2 | P34972 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203156 | 0.91 | ALDH1A1 (0.82) | ALDH1A1SMN1; SMN2TSHRHSD17B10ALOX15 | |
| SCHEMBL6200055 | 0.91 | ALDH1A1 (0.82) | ALDH1A1SMN1; SMN2TSHRHSD17B10ALOX15 | |
| SCHEMBL6205044 | 0.90 | ALDH1A1 (0.84) | ALDH1A1SMN1; SMN2TSHRHSD17B10ALOX15 | |
| SCHEMBL6202090 | 0.89 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2TSHRHSD17B10ALOX15 | |
| SCHEMBL6203815 | 0.89 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2TSHRHSD17B10ALOX15 | |
| SCHEMBL6203540 | 0.88 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2TSHRHSD17B10ALOX15 | |
| SCHEMBL6203821 | 0.88 | ALDH1A1 (0.84) | ALDH1A1SMN1; SMN2TSHRHSD17B10ALOX15 | |
| SCHEMBL6263808 | 0.88 | CNR2 (0.73) | ALDH1A1SMN1; SMN2TSHRHSD17B10ALOX15 | |
| SCHEMBL6204167 | 0.84 | LMNA (0.70) | ALDH1A1SMN1; SMN2TSHRHSD17B10ALOX15 | |
| SCHEMBL3980443 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2TSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509514-A1 | ANTHELMINTIC AND INSECTICIDAL THIOPHENE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2005-03-02 | — | — | EP | claimed |
| US-20040014740-A1 | Novel anthelmintic and insecticidal compositions | PHARMACIA & UPJOHN COMPANY | 2004-01-22 | — | — | US | claimed |
| WO-2003101979-A1 | ANTHELMINTIC AND INSECTICIDAL THIOPHENE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2003-12-11 | — | — | WO | claimed |
| EP-1509514-A1 | ANTHELMINTIC AND INSECTICIDAL THIOPHENE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2005-03-02 | — | — | EP | disclosed |
| US-20040014740-A1 | Novel anthelmintic and insecticidal compositions | PHARMACIA & UPJOHN COMPANY | 2004-01-22 | — | — | US | disclosed |
| WO-2003101979-A1 | ANTHELMINTIC AND INSECTICIDAL THIOPHENE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014740-A1 | Novel anthelmintic and insecticidal compositions | ACHE, BCHE, AADAC | ALDH1A1 2781/4885SMN1; SMN2 3997/4885TSHR 4483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.