Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201979 | 0.92 | MCL1 (0.52) | ALDH1A1MCL1POLBKDM4EMEN1 | |
| SCHEMBL6197449 | 0.92 | MCL1 (0.48) | ALDH1A1MCL1KDM4EEGLN1LMNA | |
| SCHEMBL6200211 | 0.88 | MCL1 (0.48) | ALDH1A1MCL1KDM4EMEN1KMT2A | |
| SCHEMBL6198581 | 0.88 | MCL1 (0.48) | ALDH1A1MCL1KDM4EEGLN1LMNA | |
| SCHEMBL6204188 | 0.88 | MCL1 (0.47) | ALDH1A1MCL1POLBKDM4EEGLN1 | |
| SCHEMBL6199253 | 0.87 | MCL1 (0.44) | ALDH1A1MCL1MEN1KMT2AEGLN1 | |
| SCHEMBL6201109 | 0.87 | MCL1 (0.47) | ALDH1A1MCL1SMN1; SMN2HTTPOLB | |
| SCHEMBL6202430 | 0.87 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTPOLBKDM4E | |
| SCHEMBL6200416 | 0.86 | MAPT (0.47) | ALDH1A1MCL1SMN1; SMN2KDM4EEGLN1 | |
| SCHEMBL6199917 | 0.86 | MCL1 (0.46) | ALDH1A1MCL1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |