Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201284 | 1.00 | SMYD3 (0.31) | SMYD3DPP4PREPDPP7KDM4E | |
| SCHEMBL7474500 | 0.85 | ALDH1A1 (0.34) | KDM4EALDH1A1PTPN7DUSP3 | |
| SCHEMBL7470106 | 0.77 | DPP4 (0.30) | DPP4 | |
| SCHEMBL1473973 | 0.70 | — | — | |
| SCHEMBL5387497 | 0.69 | NPY5R (0.42) | ALDH1A1 | |
| SCHEMBL5387500 | 0.69 | NPY5R (0.42) | ALDH1A1 | |
| SCHEMBL5383055 | 0.65 | GAA (0.40) | DPP4DPP7ALDH1A1 | |
| SCHEMBL7474655 | 0.65 | NPY5R (0.34) | SMYD3ALDH1A1DUSP3 | |
| SCHEMBL5121347 | 0.65 | NPY5R (0.34) | SMYD3ALDH1A1DUSP3 | |
| SCHEMBL4235584 | 0.65 | SMYD3 (0.40) | SMYD3KDM4EALDH1A1PTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194421-B1 | SELECTIVE NPY (Y5) ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2005-10-12 | — | — | EP | disclosed |
| US-6225330-B1 | Selective NPY (Y5) antagonists (tricyclics) | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-05-01 | — | — | US | disclosed |