SCHEMBL7470106

SCHEMBL7470106

CN(C(N)=S)C1CCC(C(N)S(=O)(=O)N(C)C)CC1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6201280 0.77 SMYD3 (0.31) DPP4
SCHEMBL6201284 0.77 SMYD3 (0.31) DPP4
SCHEMBL27605000 0.75
SCHEMBL4274516 0.68 FAAH (0.38)
SCHEMBL4274519 0.68 FAAH (0.38)
SCHEMBL7500559 0.68 ADH1C (0.53)
SCHEMBL7470115 0.67 NPY5R (0.34)
SCHEMBL27571128 0.66 PHGDH (0.59)
SCHEMBL5127612 0.62 SMYD3 (0.37)
Ethylamine SCHEMBL10796936 0.59 PHGDH (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1194421-A4 SELECTIVE NPY (Y5) ANTAGONISTS SYNAPTIC PHARMA CORP (US) 2002-09-11 EP disclosed
EP-1194421-A1 SELECTIVE NPY (Y5) ANTAGONISTS SYNAPTIC PHARMACEUTICAL CORPORATION (US) 2002-04-10 EP disclosed
WO-2001002379-A1 SELECTIVE NPY (Y5) ANTAGONISTS SYNAPTIC PHARMACEUTICAL CORPORATION (US) 2001-01-11 WO disclosed