Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201284 | 0.85 | SMYD3 (0.31) | ALDH1A1PTPN7KDM4EDUSP3 | |
| SCHEMBL6201280 | 0.85 | SMYD3 (0.31) | ALDH1A1PTPN7KDM4EDUSP3 | |
| SCHEMBL1544580 | 0.72 | — | — | |
| SCHEMBL7470106 | 0.72 | DPP4 (0.30) | — | |
| SCHEMBL4265226 | 0.68 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2POLBRECQLCYP2D6 | |
| SCHEMBL4266940 | 0.68 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2POLBRECQLCYP2D6 | |
| SCHEMBL14564699 | 0.64 | CYP3A4 (0.68) | ALDH1A1SMN1; SMN2POLBCYP2D6RAB9A | |
| SCHEMBL8396968 | 0.64 | — | — | |
| SCHEMBL8395652 | 0.63 | CYP3A4 (0.73) | ALDH1A1DUSP3SMN1; SMN2POLBRAB9A | |
| SCHEMBL19705886 | 0.63 | CYP3A4 (0.73) | ALDH1A1DUSP3SMN1; SMN2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194421-A4 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMA CORP (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1194421-A1 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001002379-A1 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |