Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334088 | 0.84 | DHODH (0.53) | HSD17B10TSHRNPC1RAB9AKDM4E | |
| SCHEMBL9899201 | 0.82 | NR4A2 (0.46) | HSD17B10TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL1009498 | 0.82 | TSHR (0.48) | HSD17B10TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL6131949 | 0.81 | KDM4E (0.49) | HSD17B10TSHRNPC1RAB9AKDM4E | |
| SCHEMBL6200456 | 0.81 | HSD17B10 (0.42) | HSD17B10NPC1RAB9ATNKSKDM4E | |
| SCHEMBL3137352 | 0.80 | SLC6A3 (0.49) | HSD17B10TSHRRAB9AKDM4EALDH1A1 | |
| SCHEMBL9899016 | 0.78 | NR4A2 (0.50) | HSD17B10TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL1010947 | 0.77 | DHODH (0.48) | HSD17B10TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL1011786 | 0.74 | DHODH (0.45) | HSD17B10TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL3242562 | 0.74 | HSD17B10 (0.49) | HSD17B10TSHRNPC1RAB9ATNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958514-B1 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-0958514-A4 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | PPG IND OHIO INC (US) | 2000-03-22 | — | — | EP | disclosed |
| EP-0958514-A1 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | PPG Industries Ohio, Inc. (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998032037-A1 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 1998-07-23 | — | — | WO | disclosed |
| US-5698141-A | REVERSE CHARGE IN COLOR WHEN EXPOSURED TO ELECTROMAGNETIC RADIATION | PPG INDUSTRIES, INC. (US) | 1997-12-16 | — | — | US | disclosed |