Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25539406 | 0.93 | HTR1A (0.48) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL25846133 | 0.82 | HRH3 (0.49) | ALDH1A1NPC1RAB9AKDM4EGRM5 | |
| SCHEMBL9047388 | 0.80 | HTR1A (0.72) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL2493210 | 0.80 | HTR6 (0.51) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL30337054 | 0.80 | HTR1A (0.67) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL16046661 | 0.79 | HTR1A (0.74) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL17659018 | 0.77 | HTR1A (0.52) | HTR1ASLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL19381657 | 0.77 | MEN1 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL19381661 | 0.77 | MEN1 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL19381141 | 0.77 | MEN1 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532132-A1 | NOVEL BENZODIOXOLES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004013120-A1 | NOVEL BENZODIOXOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-12 | — | — | WO | disclosed |