Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17007463 | 0.92 | ALDH1A1 (0.75) | ALDH1A1LMNAPKMMEN1KMT2A | |
| SCHEMBL2360974 | 0.83 | ALDH1A1 (0.84) | ALDH1A1LMNAPKMMEN1KMT2A | |
| SCHEMBL5347059 | 0.80 | ALDH1A1 (0.97) | ALDH1A1LMNAPKMMEN1KMT2A | |
| SCHEMBL28137833 | 0.79 | ALDH1A1 (1.00) | ALDH1A1LMNAPKMMEN1KMT2A | |
| SCHEMBL7589260 | 0.78 | POLB (0.64) | ALDH1A1LMNAPKMMEN1KMT2A | |
| SCHEMBL7589283 | 0.78 | POLB (0.64) | ALDH1A1LMNAPKMMEN1KMT2A | |
| SCHEMBL7647475 | 0.77 | ALDH1A1 (0.75) | ALDH1A1LMNAPKMMEN1KMT2A | |
| SCHEMBL9976087 | 0.76 | ALDH1A1 (0.73) | ALDH1A1LMNAPKMMEN1KMT2A | |
| SCHEMBL2061369 | 0.76 | PKM (0.76) | ALDH1A1LMNAPKMMEN1KMT2A | |
| SCHEMBL2062534 | 0.76 | POLB (0.75) | ALDH1A1LMNAPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381392-A4 | SYNTHETIC CATALYST FOR SELECTIVE CLEAVAGE OF PROTEIN AND METHOD FOR SELECTIVE CLEAVAGE OF PROTEIN USING THE SAME | TS CORP (KR) | 2005-03-23 | — | — | EP | disclosed |
| EP-1381392-A1 | SYNTHETIC CATALYST FOR SELECTIVE CLEAVAGE OF PROTEIN AND METHOD FOR SELECTIVE CLEAVAGE OF PROTEIN USING THE SAME | TS Corporation (KR) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002085413-A1 | SYNTHETIC CATALYST FOR SELECTIVE CLEAVAGE OF PROTEIN AND METHOD FOR SELECTIVE CLEAVAGE OF PROTEIN USING THE SAME | TS CORPORATION (KR) | 2002-10-31 | — | — | WO | disclosed |