Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589283 | 1.00 | POLB (0.64) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL17007463 | 0.85 | ALDH1A1 (0.75) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL2360974 | 0.80 | ALDH1A1 (0.84) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL6201775 | 0.78 | ALDH1A1 (0.64) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL18230449 | 0.78 | KMT2A (0.69) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL18230447 | 0.78 | KMT2A (0.69) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL7527409 | 0.78 | POLB (0.72) | POLBPKMKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6094287 | 0.76 | POLB (0.69) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL14477865 | 0.74 | PKM (0.69) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL5347059 | 0.74 | ALDH1A1 (0.97) | POLBPKMKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020165365-A1 | Synthetic catalyst for selective cleavage of protein and method for selective cleavage of protein using the same | ARTZYME BIOTECH CORPORATION (KR) | 2002-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165365-A1 | Synthetic catalyst for selective cleavage of protein and method for selective cleavage of protein using the same | CPN1, RNPEP, ANPEP | POLB 2983/4885PKM 3939/4885KMT2A 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.