Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | PNLIP | P16233 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198759 | 0.88 | GAA (0.38) | GAAALDH1A1LMNAPTGS2AURKA | |
| SCHEMBL6202705 | 0.85 | GAA (0.36) | GAAALDH1A1LMNAPTGS2AURKA | |
| SCHEMBL6203097 | 0.84 | GAA (0.44) | GAAALDH1A1LMNAPTGS2AURKA | |
| SCHEMBL6200932 | 0.82 | GAA (0.41) | TET2GAAALDH1A1LMNAPTGS2 | |
| SCHEMBL6198572 | 0.69 | PTGS2 (0.44) | GAAALDH1A1LMNAPTGS2MAPT | |
| SCHEMBL6196896 | 0.69 | EGLN1 (0.47) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL6198567 | 0.67 | GAA (0.43) | GAAALDH1A1LMNAPTGS2KMT2A | |
| SCHEMBL6200560 | 0.65 | GAA (0.52) | GAAALDH1A1LMNAPTGS2MAPT | |
| SCHEMBL27471079 | 0.65 | TET2 (0.40) | TET2KDM4E | |
| SCHEMBL27433136 | 0.64 | TET2 (0.40) | TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |