Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198759 | 0.84 | GAA (0.38) | GAAFNTAFNTBPTGS2ATM | |
| SCHEMBL6201873 | 0.84 | TET2 (0.34) | GAAFNTAFNTBPTGS2ATM | |
| SCHEMBL6202705 | 0.84 | GAA (0.36) | GAAFNTAFNTBPTGS2ATM | |
| SCHEMBL6200560 | 0.81 | GAA (0.52) | GAAGRM5PTGS2ALDH1A1CYP1A2 | |
| SCHEMBL6198854 | 0.68 | EGLN1 (0.54) | TRPA1ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6204065 | 0.68 | GAA (0.47) | GAAPTGS2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6200932 | 0.65 | GAA (0.41) | GAAPTGS2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6198572 | 0.65 | PTGS2 (0.44) | GAAPTGS2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1504425 | 0.65 | PTGS2 (0.58) | GAAPTGS2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6198567 | 0.65 | GAA (0.43) | GAAPTGS2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |