Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | DDO | Q99489 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | PNLIP | P16233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198759 | 0.85 | GAA (0.38) | GAAALDH1A1LMNAPTGS2AURKA | |
| SCHEMBL6201873 | 0.85 | TET2 (0.34) | GAAALDH1A1LMNAPTGS2AURKA | |
| SCHEMBL6203097 | 0.84 | GAA (0.44) | GAAALDH1A1LMNAPTGS2AURKA | |
| SCHEMBL6198567 | 0.81 | GAA (0.43) | GAAALDH1A1LMNAPTGS2SMN1; SMN2 | |
| SCHEMBL6198591 | 0.67 | EGLN1 (0.49) | ALDH1A1LMNASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL6198572 | 0.67 | PTGS2 (0.44) | GAAALDH1A1LMNAPTGS2NPC1 | |
| SCHEMBL6200932 | 0.67 | GAA (0.41) | GAAALDH1A1LMNAPTGS2TDP1 | |
| SCHEMBL10590600 | 0.65 | CUL4A (0.34) | ALDH1A1LMNAKCNQ3KCNQ2POLB | |
| SCHEMBL6200560 | 0.65 | GAA (0.52) | GAAALDH1A1LMNAPTGS2SMN1; SMN2 | |
| SCHEMBL6201203 | 0.63 | KDM4E (0.41) | ALDH1A1ALOX12RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |