Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 14/20 | 0.42 |
| ▸ | TDO2 | P48775 | 10/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203172 | 1.00 | IDO1 (0.42) | IDO1TDO2IDO2DPP4F2 | |
| SCHEMBL6202821 | 1.00 | IDO1 (0.42) | IDO1TDO2IDO2DPP4F2 | |
| Hydrochloric Acid SCHEMBL7227164 | 0.98 | IDO1 (0.44) | IDO1TDO2IDO2 | |
| Hydrochloric Acid SCHEMBL7232949 | 0.98 | IDO1 (0.44) | IDO1TDO2IDO2 | |
| Hydrochloric Acid SCHEMBL7227095 | 0.98 | IDO1 (0.44) | IDO1TDO2IDO2 | |
| SCHEMBL77245 | 0.81 | DPP4 (0.36) | IDO1TDO2IDO2DPP4F2 | |
| SCHEMBL6203275 | 0.78 | IDO1 (0.54) | IDO1TDO2 | |
| SCHEMBL6201361 | 0.78 | CHRNA7 (0.35) | IDO1TDO2 | |
| SCHEMBL5329740 | 0.77 | TRPA1 (0.46) | IDO1TDO2IDO2DPP4F2 | |
| SCHEMBL8692714 | 0.77 | THRB (0.40) | DPP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266887-B1 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-08-17 | — | — | EP | disclosed |
| CN-1390834-A | Indenoindolone compounds, their preparation and medicinal compositions containing them | SEUVILE LAB (FR) | 2003-01-15 | — | — | CN | disclosed |
| EP-1266887-A2 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-12-18 | — | — | EP | disclosed |