Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224772 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HDAC1HDAC8HDAC6DDB1 | |
| SCHEMBL4224776 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HDAC1HDAC8HDAC6DDB1 | |
| Hydrochloric Acid SCHEMBL7933795 | 0.98 | ALDH1A1 (0.46) | ALDH1A1HDAC1HDAC8HDAC6DDB1 | |
| Hydrochloric Acid SCHEMBL6818480 | 0.98 | ALDH1A1 (0.46) | ALDH1A1HDAC1HDAC8HDAC6DDB1 | |
| Hydrochloric Acid SCHEMBL7927419 | 0.98 | ALDH1A1 (0.46) | ALDH1A1HDAC1HDAC8HDAC6DDB1 | |
| SCHEMBL20570052 | 0.91 | ENPP2 (0.50) | L3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL6202280 | 0.90 | L3MBTL1 (0.51) | ALDH1A1HDAC1HDAC8HDAC6DDB1 | |
| SCHEMBL3245339 | 0.89 | L3MBTL1 (0.54) | ALDH1A1DDB1CRBNL3MBTL1KMT2A | |
| SCHEMBL3618774 | 0.89 | L3MBTL1 (0.54) | ALDH1A1DDB1CRBNL3MBTL1KMT2A | |
| SCHEMBL3245199 | 0.89 | L3MBTL1 (0.54) | ALDH1A1DDB1CRBNL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684953-B1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | KANEKA CORP (JP) | 2017-06-28 | — | — | EP | disclosed |
| CN-103534353-B | Modification type aminopherase, its gene and utilize their manufacture method of optical activity amino-compound | 株式会社钟化 | 2016-08-17 | — | — | CN | disclosed |
| US-9029113-B2 | Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same | KANEKA CORPORATION (JP) | 2015-05-12 | — | — | US | disclosed |
| CN-103534353-A | Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same | KANEKA CORP | 2014-01-22 | — | — | CN | disclosed |
| EP-2684953-A1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | Kaneka Corporation (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-20140004575-A1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | KANEKA CORPORATION (JP) | 2014-01-02 | — | — | US | disclosed |
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |