Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198303 | 0.88 | EGLN1 (0.43) | NR3C1LMNAEGLN1POLA1SMN1; SMN2 | |
| SCHEMBL6198300 | 0.86 | LMNA (0.40) | NR3C1LMNAEGLN1POLA1SMN1; SMN2 | |
| SCHEMBL6197282 | 0.84 | EGLN1 (0.41) | NR3C1LMNAEGLN1POLA1SMN1; SMN2 | |
| SCHEMBL6199600 | 0.83 | EGLN1 (0.45) | NR3C1EGLN1POLA1CYP1A2CYP2C19 | |
| SCHEMBL6199591 | 0.82 | NR3C1 (0.38) | NR3C1LMNAEGLN1POLA1SMN1; SMN2 | |
| SCHEMBL6200817 | 0.82 | NR3C1 (0.49) | NR3C1LMNAEGLN1POLA1CYP1A2 | |
| SCHEMBL6200673 | 0.80 | POLA1 (0.41) | NR3C1LMNAEGLN1POLA1SMN1; SMN2 | |
| SCHEMBL6198849 | 0.80 | EGLN1 (0.51) | NR3C1LMNAEGLN1POLA1SMN1; SMN2 | |
| SCHEMBL6198701 | 0.79 | POLA1 (0.41) | NR3C1LMNAEGLN1POLA1SMN1; SMN2 | |
| SCHEMBL6198751 | 0.79 | CYP1A2 (0.55) | NR3C1LMNAEGLN1POLA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |