Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900350 | 0.79 | THRB (0.61) | THRBKDM4EHPGDMAPTTSHR | |
| SCHEMBL1009517 | 0.79 | THRB (0.65) | THRBKDM4EHPGDALDH1A1LMNA | |
| SCHEMBL16363434 | 0.77 | MAPT (0.57) | KDM4EHPGDGLAALDH1A1LMNA | |
| SCHEMBL21450734 | 0.77 | MAPT (0.57) | KDM4EHPGDGLAALDH1A1LMNA | |
| SCHEMBL29522832 | 0.76 | HPGD (0.52) | KDM4EHPGDGLAALDH1A1LMNA | |
| SCHEMBL126888 | 0.76 | HPGD (0.52) | KDM4EHPGDGLAALDH1A1LMNA | |
| SCHEMBL21450766 | 0.76 | MAPT (0.55) | KDM4EHPGDGLAALDH1A1LMNA | |
| SCHEMBL21450760 | 0.76 | MAPT (0.55) | KDM4EHPGDGLAALDH1A1LMNA | |
| SCHEMBL1711104 | 0.76 | THRB (0.56) | THRBKDM4EHPGDALDH1A1GAA | |
| SCHEMBL28816389 | 0.75 | TBK1 (0.56) | KDM4EHPGDGLAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958514-B1 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-0958514-A4 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | PPG IND OHIO INC (US) | 2000-03-22 | — | — | EP | disclosed |
| EP-0958514-A1 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | PPG Industries Ohio, Inc. (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998032037-A1 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 1998-07-23 | — | — | WO | disclosed |
| US-5698141-A | REVERSE CHARGE IN COLOR WHEN EXPOSURED TO ELECTROMAGNETIC RADIATION | PPG INDUSTRIES, INC. (US) | 1997-12-16 | — | — | US | disclosed |