Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209213 | 0.85 | ADRA2C (0.43) | FFAR4ADRA2CADRA1AADRA1BFFAR1 | |
| SCHEMBL7068506 | 0.85 | HPGD (0.49) | FFAR4ADRA2CADRA1AADRA1BMAPT | |
| SCHEMBL1462084 | 0.81 | CYP3A4 (0.48) | — | |
| SCHEMBL831738 | 0.80 | FFAR4 (0.42) | FFAR4ADRA2CADRA1AADRA1BKMT2A | |
| Ammonia Solution, Strong SCHEMBL2209211 | 0.76 | ADRA2C (0.55) | FFAR4ADRA2CADRA1AADRA1BHPGD | |
| SCHEMBL6200524 | 0.75 | ALDH1A1 (0.54) | FFAR4KMT2AMAPTSMN1; SMN2CA1 | |
| SCHEMBL2908147 | 0.72 | CA1 (0.57) | KMT2AHPGDSMN1; SMN2CA1CA2 | |
| SCHEMBL14115705 | 0.72 | FFAR4 (0.77) | FFAR4KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL6202490 | 0.72 | KMT2A (0.38) | FFAR4KMT2ATHRBHPGDCA1 | |
| SCHEMBL10786767 | 0.70 | KMT2A (0.49) | KMT2ATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973739-B1 | N-ARYLSULFONAMIDE- AND PYRROLIDINECARBOXYLIC ACID INTERMEDIATES, AND THEIR USE FOR THE PREPARATION OF HERBICIDAL 1,3-DIOXO-1H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES | DEGUSSA (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-6664400-B2 | 1-((4-halo-3-sulfonamidophenyl)aminocarbonyl),2-carboxy -pyrrolidine intermediate of given formula | DEGUSSA AG (DE) | 2003-12-16 | — | — | US | disclosed |
| US-20020137946-A1 | N-arylsulfonamide and pyrrolidinecarboxylic acid intermediates, and their use for the preparation of herbicidal 1,3-dioxo-1h-pyrrolo[1,2-c]imidazole derivatives | DEGUSSA AG (DE) | 2002-09-26 | — | — | US | disclosed |
| US-6384234-B1 | HALOGENATION | DEGUSSA AG (DE) | 2002-05-07 | — | — | US | disclosed |
| CN-1248244-A | N-arylsulfonamide- and pyrrolidinecarboxylic acid intermediates, and their use for preparation of herbicidal 1,3-dioxo-1H-pyrrolo [1,2-c] imidazole derivatives | DU PONT (US) | 2000-03-22 | — | — | CN | disclosed |
| EP-0973739-A1 | N-ARYLSULFONAMIDE- AND PYRROLIDINECARBOXYLIC ACID INTERMEDIATES, AND THEIR USE FOR THE PREPARATION OF HERBICIDAL 1,3-DIOXO-1H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998037065-A1 | N-ARYLSULFONAMIDE- AND PYRROLIDINECARBOXYLIC ACID INTERMEDIATES, AND THEIR USE FOR THE PREPARATION OF HERBICIDAL 1,3-DIOXO-1H-PYRROLO[1,2-C]IMIDAZOLE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137946-A1 | N-arylsulfonamide and pyrrolidinecarboxylic acid intermediates, and their use for the preparation of herbicidal 1,3-dioxo-1h-pyrrolo[1,2-c]imidazole derivatives | CBR3, CBR1, CLIC1 | FFAR4 873/4885ADRA2C 1150/4885ADRA1A 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.