Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | CA12 | O43570 | 4/20 | 0.68 |
| ▸ | CA1 | P00915 | 4/20 | 0.68 |
| ▸ | CA2 | P00918 | 4/20 | 0.68 |
| ▸ | CA7 | P43166 | 4/20 | 0.68 |
| ▸ | CA9 | Q16790 | 4/20 | 0.68 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.68 |
| ▸ | ALPL | P05186 | 2/20 | 0.67 |
| ▸ | ALPG | P10696 | 2/20 | 0.67 |
| ▸ | ALPI | P09923 | 1/20 | 0.67 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.67 |
| ▸ | MGAM | O43451 | 1/20 | 0.63 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | SI | P14410 | 1/20 | 0.63 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.63 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.58 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.58 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18825270 | 0.88 | CA12 (0.71) | RAB9ACA12CA1CA2CA7 | |
| SCHEMBL6201409 | 0.86 | CA12 (0.68) | RAB9ACA12CA1CA2CA7 | |
| SCHEMBL1718552 | 0.85 | CDYL2 (0.68) | RAB9ACA12CA1CA2CA7 | |
| SCHEMBL10247491 | 0.81 | KDM4E (0.51) | RAB9ACA12CA1CA2CA7 | |
| SCHEMBL22381006 | 0.81 | CA12 (1.00) | RAB9ACA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL1775490 | 0.80 | ALPL (0.50) | RAB9ACA12CA1CA2CA7 | |
| SCHEMBL1036975 | 0.80 | SMN1; SMN2 (0.68) | KDM4ENPC1SMN1; SMN2F10F2 | |
| SCHEMBL8019373 | 0.78 | RAB9A (0.51) | RAB9ACA12CA1CA2CA7 | |
| SCHEMBL7366448 | 0.78 | RAB9A (0.51) | RAB9ACA12CA1CA2CA7 | |
| SCHEMBL1035783 | 0.77 | EGLN3 (0.71) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |