Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 6/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1953700 | 0.82 | L3MBTL1 (0.54) | ALDH1A1MAPTTHRBNPSR1L3MBTL1 | |
| SCHEMBL1951621 | 0.81 | HPGD (0.40) | ALDH1A1MAPTKCNH2NPSR1 | |
| SCHEMBL1205405 | 0.78 | HTT (0.49) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL16437110 | 0.78 | L3MBTL1 (0.48) | ALDH1A1MAPTHIF1ANPSR1L3MBTL1 | |
| SCHEMBL10701443 | 0.78 | L3MBTL1 (0.56) | CACNA1GCACNA1HCACNA1IALDH1A1MAPT | |
| SCHEMBL30447174 | 0.78 | SLC6A4 (0.41) | — | |
| SCHEMBL1548220 | 0.78 | SLC6A4 (0.41) | — | |
| SCHEMBL8048270 | 0.76 | HTR2C (0.42) | CACNA1GCACNA1HCACNA1IALDH1A1MAPT | |
| SCHEMBL4129639 | 0.76 | HTR1A (0.56) | ALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL12394754 | 0.74 | GABRA1 (0.45) | CACNA1GCACNA1HCACNA1IALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562937-A2 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | Acadia Pharmaceuticals Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004000808-A2 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | ACADIA PHARMACEUTICALS INC. (US) | 2003-12-31 | — | — | WO | disclosed |