Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30592112 | 0.79 | KMT2A (0.60) | DDB1CRBNALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL19585683 | 0.78 | CRBN (1.00) | DDB1CRBNALDH1A1HDAC6MEN1 | |
| SCHEMBL14476487 | 0.77 | ALDH1A1 (0.69) | DDB1CRBNALDH1A1KLK5SMN1; SMN2 | |
| SCHEMBL21182827 | 0.75 | EPHX2 (0.53) | DDB1CRBNALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29271799 | 0.75 | HPGD (0.55) | DDB1CRBNALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31730127 | 0.75 | ALDH1A1 (0.66) | ALDH1A1KLK5SMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL16208261 | 0.74 | DDB1 (0.52) | DDB1CRBNSMN1; SMN2HDAC6MEN1 | |
| SCHEMBL10742560 | 0.73 | CYP1A2 (0.68) | DDB1CRBNALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22015866 | 0.73 | L3MBTL1 (0.44) | ALDH1A1KLK5SMN1; SMN2HDAC6HDAC3 | |
| SCHEMBL7072835 | 0.73 | HPGD (0.56) | DDB1CRBNSMN1; SMN2HDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556346-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-27 | — | — | EP | claimed |
| WO-2004037787-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-06 | — | — | WO | claimed |
| EP-1556346-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037787-A1 | 1-PHENYLPYRROLIDINE-2-ONE-3-CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-06 | — | — | WO | disclosed |