Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909307 | 1.00 | VNN1 (0.52) | VNN1CNR2CNR1GRM5GAA | |
| SCHEMBL5909193 | 1.00 | VNN1 (0.52) | VNN1CNR2CNR1GRM5GAA | |
| SCHEMBL5909277 | 0.84 | ALDH1A1 (0.60) | CNR2CNR1ALDH1A1 | |
| SCHEMBL6275232 | 0.84 | ALDH1A1 (0.60) | CNR2CNR1ALDH1A1 | |
| SCHEMBL5909210 | 0.82 | CNR2 (0.48) | VNN1CNR2HPGDALDH1A1JAK2 | |
| SCHEMBL5909207 | 0.82 | CNR2 (0.48) | VNN1CNR2HPGDALDH1A1JAK2 | |
| SCHEMBL5909232 | 0.81 | ALDH1A1 (0.48) | VNN1CNR2CNR1GRM5ALDH1A1 | |
| SCHEMBL5909241 | 0.80 | ALDH1A1 (0.52) | VNN1GAAHPGDALDH1A1SPHK2 | |
| SCHEMBL5909250 | 0.80 | ALDH1A1 (0.52) | VNN1GAAHPGDALDH1A1SPHK2 | |
| SCHEMBL17600726 | 0.80 | GRM5 (0.55) | VNN1CNR2CNR1GRM5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494672-A1 | AMINOCARBONYL SUBSTITUTED PYRIDINES, PYRIDAZINES, PYRIMIDINES, PYRAZINES AND TRIAZINES HAVING ANTIANGIOGENIC ACTIVITY | Abbott Laboratories (US) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003086398-A1 | AMINOCARBONYL SUBSTITUTED PYRIDINES, PYRIDAZINES, PYRIMIDINES, PYRAZINES AND TRIAZINES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LABORATORIES (US) | 2003-10-23 | — | — | WO | disclosed |