SCHEMBL6203458

SCHEMBL6203458

O=C(O)Oc1ccccc1S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HTR6 P50406 1/20 0.39
MAPT P10636 4/20 0.39
ALDH1A1 P00352 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
MYC P01106 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ELANE P08246 1/20 0.37
TTR P02766 2/20 0.37
FABP4 P15090 2/20 0.37
CCNA2 P20248 1/20 0.37
CDK2 P24941 1/20 0.37
MAPK14 Q16539 1/20 0.37
KDM4E B2RXH2 3/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allylamine SCHEMBL9637414 0.86 CYP1A2 (0.36) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL6203454 0.86 HSD17B10 (0.39) TSHRSMN1; SMN2HTR6MAPTALDH1A1
SCHEMBL31098906 0.83 KMT2A (0.58) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL38811 0.83 KMT2A (0.58) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL9323714 0.82 MYC (0.37) TSHRSMN1; SMN2HTR6MAPTALDH1A1
SCHEMBL5157706 0.82 CA2 (0.47) CYP2C9CDK2HSD17B10CA1CA2
SCHEMBL3018679 0.82 PTGS2 (0.52) TSHRMAPTALDH1A1KMT2ALMNA
SCHEMBL29753992 0.82 PTGS2 (0.52) TSHRMAPTALDH1A1KMT2ALMNA
SCHEMBL8899315 0.82 CYP1A2 (0.43) TSHRSMN1; SMN2HTR6MAPTALDH1A1
SCHEMBL8634038 0.81 MYC (0.36) TSHRSMN1; SMN2HTR6MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0653485-B1 Detergent composition UNILEVER NV (NL) 2000-05-17 EP claimed
EP-0227194-B1 PREPARATION OF SULPHONATED AROMATIC ESTERS UNILEVER N.V. (NL) 1989-08-23 EP claimed
US-4788316-A Preparation of sulphonated aromatic esters LEVER BROTHERS COMPANY (US) 1988-11-29 US claimed
EP-0227194-A1 Preparation of sulphonated aromatic esters UNILEVER N.V. (NL) 1987-07-01 EP claimed
US-20250345579-A1 Biological Tissue Transdermal Patch NIPPON TELEGRAPH & TELEPHONE (JP) 2025-11-13 US disclosed
EP-1506277-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2005-02-16 EP disclosed
WO-2003097780-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2003-11-27 WO disclosed
WO-1999057233-A1 PERFUME COMPOSITION QUEST INTERNATIONAL B.V. (NL) 1999-11-11 WO disclosed
CN-1045310-C Detergent compositions UNILEVER NV (NL) 1999-09-29 CN disclosed
CN-1045311-C Detergent compositions UNILEVER NV (NL) 1999-09-29 CN disclosed
US-5314635-A Macrocyclic organonitrogen ligand LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1994-05-24 US disclosed
CN-1074705-A Detergent composition UNILEVER NV (NL) 1993-07-28 CN disclosed
EP-0549271-A1 Bleach activation UNILEVER PLC (GB) 1993-06-30 EP disclosed
US-5124475-A Preparation of p-phenyl sulfonate esters of acyl glycolic acids STEPAN COMPANY (US) 1992-06-23 US disclosed
EP-0414655-A1 Improved process for the production of carbonate esters MONSANTO COMPANY (US) 1991-02-27 EP disclosed
EP-0227194-B1 PREPARATION OF SULPHONATED AROMATIC ESTERS UNILEVER N.V. (NL) 1989-08-23 EP disclosed
US-4788316-A Preparation of sulphonated aromatic esters LEVER BROTHERS COMPANY (US) 1988-11-29 US disclosed
US-4788316-A Preparation of sulphonated aromatic esters LEVER BROTHERS COMPANY (US) 1988-11-29 US disclosed
EP-0227194-A1 Preparation of sulphonated aromatic esters UNILEVER N.V. (NL) 1987-07-01 EP disclosed
EP-0227194-A1 Preparation of sulphonated aromatic esters UNILEVER N.V. (NL) 1987-07-01 EP disclosed