SCHEMBL9323714

SCHEMBL9323714

O=C(Cl)Oc1ccccc1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.37
ELANE P08246 2/20 0.36
TSHR P16473 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TTR P02766 2/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 3/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
HTR6 P50406 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
FABP4 P15090 2/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
MAPK14 Q16539 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA5A P35218 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5175246 0.85 TRPV4 (0.37) ELANETSHRSMN1; SMN2ALDH1A1MAPT
SCHEMBL6203454 0.84 HSD17B10 (0.39) MYCELANETSHRSMN1; SMN2TTR
SCHEMBL5175522 0.83 CA1 (0.46) CYP2C9CDK2CA1CA2CA5A
SCHEMBL11199429 0.83 BCAT2 (0.40) ELANEKMT2ALMNAHTR6CYP1A2
SCHEMBL6203458 0.82 TSHR (0.41) MYCELANETSHRSMN1; SMN2TTR
SCHEMBL29753992 0.81 PTGS2 (0.52) MYCTSHRALDH1A1MAPTKMT2A
SCHEMBL3018679 0.81 PTGS2 (0.52) MYCTSHRALDH1A1MAPTKMT2A
SCHEMBL10499169 0.80 ACLY (0.36) MYCELANETSHRSMN1; SMN2TTR
SCHEMBL8380237 0.79 PTGS2 (0.50) TSHRALDH1A1MAPTKMT2ALMNA
SCHEMBL8634038 0.79 MYC (0.36) MYCELANETSHRSMN1; SMN2TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-204429259-U For the easy-cleaning type soaking reactor of sulfo-phenyl chloroformate esterification YIBIN JIULING CHEMICAL CORP 2015-07-01 CN claimed
CN-103764661-A Novel pyrimidine derivative and pharmaceutical composition containing same as active ingredient HANMI PHARM IND CO LTD 2014-04-30 CN claimed
CN-101671288-B Preparation method of intermediate of paricalcitol UNIV LANZHOU 2013-10-30 CN claimed
CN-103739645-B A kind of preparation method of Decitabine SHANDONG NEW TIME PHARMACEUTICAL Co.,Ltd. (CN) 2016-05-25 CN disclosed
CN-102596915-B The synthetic method of 2-thiolhistidine and analogue TETRAHEDRON (FR) 2016-04-20 CN disclosed
CN-102458581-B N- (hetero) aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo [2, 3-d ] pyrimidines and pyrrol-3-yl-pyrrolo [2, 3-d ] pyrimidines as JANUS kinase inhibitors INCYTE HOLDINGS CORP. (US) 2016-03-30 CN disclosed
CN-103739636-B A kind of preparation method of Decitabine intermediate SHANDONG NEW TIME PHARMACEUTICAL Co.,Ltd. (CN) 2016-02-03 CN disclosed
CN-103221389-B The manufacture method of isothiocyanate compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-01-20 CN disclosed
CN-101626683-B Be used for the treatment of compound and the pharmaceutical composition of virus infection IDENIX PHARMACEUTICALS, INC. (US) 2015-08-19 CN disclosed
CN-104844490-A Method for greenly synthesizing isothiocyanate through two-step method UNIV CHANGZHOU 2015-08-19 CN disclosed
CN-204429259-U For the easy-cleaning type soaking reactor of sulfo-phenyl chloroformate esterification YIBIN JIULING CHEMICAL CORP 2015-07-01 CN disclosed
CN-1113871-C 9-aminoacridine derivatives and process for preparing same SAMJIN PHARM CO LTD (KR) 2003-07-09 CN disclosed
CN-1291189-A 9-aminoacridine derivatives and process for preparing same SAMJIN PHARM CO LTD (KR) 2001-04-11 CN disclosed
CN-1026048-C Use of solsonylurea compounds as herbicide TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1994-10-05 CN disclosed
EP-0415473-B1 Process for preparing sulphophenyl carbonate esters UNILEVER NV (NL) 1994-02-09 EP disclosed
CN-1018643-B Process for producing sulfonylurea compound TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1992-10-14 CN disclosed
CN-1059073-A Solsonylurea compounds is as the purposes of weed killer herbicide TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1992-03-04 CN disclosed
EP-0415473-A1 Process for preparing sulphophenyl carbonate esters UNILEVER N.V. (NL) 1991-03-06 EP disclosed
US-4985561-A Sulfur trioxide sulfonation of aromatic chloroformates LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-01-15 US disclosed
CN-87102123-A Sulfonylurea compounds, their preparation and their use as herbicides 1987-10-21 CN disclosed