Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677772 | 0.72 | — | — | |
| SCHEMBL27583030 | 0.63 | TSHR (0.47) | LMNAKDM4ETSHRALDH1A1ALOX15 | |
| Biphenyl SCHEMBL1394409 | 0.62 | TSHR (0.53) | LMNAKDM4EGAAMAPTTSHR | |
| Urethane SCHEMBL3261529 | 0.61 | ALOX15 (0.58) | LMNACYP1A2CYP3A4MAOAKDM4E | |
| SCHEMBL3824966 | 0.60 | HDAC4 (0.63) | LMNACYP1A2CYP3A4MAOAKDM4E | |
| SCHEMBL3508602 | 0.60 | CA12 (0.62) | LMNACYP1A2CYP3A4MAOAKDM4E | |
| SCHEMBL31376339 | 0.60 | KDM4E (0.46) | LMNACYP1A2CYP3A4MAOAKDM4E | |
| Urethane SCHEMBL27931900 | 0.59 | — | — | |
| SCHEMBL11008658 | 0.59 | ALDH1A1 (0.62) | LMNACYP3A4KDM4EGAAMAPT | |
| SCHEMBL1664013 | 0.59 | CA12 (0.75) | LMNACYP1A2CYP3A4MAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532132-A1 | NOVEL BENZODIOXOLES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004013120-A1 | NOVEL BENZODIOXOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-12 | — | — | WO | disclosed |