Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22215188 | 0.88 | TDP1 (0.53) | MDM2KMT2AMEN1GAAATM | |
| SCHEMBL28987199 | 0.86 | MDM2 (0.58) | MDM2KMT2AMEN1GAAATM | |
| SCHEMBL28987197 | 0.86 | MDM2 (0.58) | MDM2KMT2AMEN1GAAATM | |
| SCHEMBL31258302 | 0.85 | MMP8 (0.47) | MDM2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1696047 | 0.85 | MDM2 (0.48) | MDM2KMT2AMEN1GAAATM | |
| SCHEMBL17664140 | 0.84 | RAB9A (0.56) | MDM2KMT2AMEN1GAAS1PR4 | |
| SCHEMBL31258304 | 0.84 | MAPT (0.51) | MDM2KMT2AMEN1PTGS2NPC1 | |
| SCHEMBL28987198 | 0.81 | MDM2 (0.56) | MDM2KMT2AMEN1PTGS2NPC1 | |
| SCHEMBL22215228 | 0.80 | ALDH1A1 (0.64) | MDM2KMT2AMEN1GAAPTGS2 | |
| SCHEMBL28987193 | 0.80 | ALDH1A1 (0.64) | MDM2KMT2AMEN1GAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119100940-A | Green synthesis method for preparing chiral alpha-aminoketone under illumination | 中山大学 | 2024-12-10 | — | — | CN | disclosed |
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |