Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204909 | 0.73 | NPC1 (0.31) | NPC1TSHRRAB9A | |
| SCHEMBL6202685 | 0.72 | TSHR (0.32) | NPC1TSHRRAB9A | |
| SCHEMBL6203544 | 0.71 | NPC1 (0.32) | NPC1TSHRRAB9A | |
| SCHEMBL948252 | 0.71 | ALDH1A1 (0.46) | NPC1TSHRRAB9A | |
| SCHEMBL3365813 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL12634094 | 0.68 | TDP1 (0.36) | — | |
| SCHEMBL3364687 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL4104587 | 0.67 | KDM4E (0.40) | NPC1RAB9A | |
| SCHEMBL11604002 | 0.66 | KDM4E (0.38) | NPC1RAB9A | |
| SCHEMBL11908618 | 0.66 | ALDH1A1 (0.49) | NPC1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501877-A1 | FLUORINATED POLYMERS | Honeywell International Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| US-20040126695-A1 | Fluorinated polymers | HONEYWELL INTERNATIONAL, INC. | 2004-07-01 | — | — | US | claimed |
| WO-2003095505-A1 | FLUORINATED POLYMERS | HONEYWELL INTERNATIONAL INC. (US) | 2003-11-20 | — | — | WO | claimed |
| EP-1501877-A1 | FLUORINATED POLYMERS | Honeywell International Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040126695-A1 | Fluorinated polymers | HONEYWELL INTERNATIONAL, INC. | 2004-07-01 | — | — | US | disclosed |
| WO-2003095505-A1 | FLUORINATED POLYMERS | HONEYWELL INTERNATIONAL INC. (US) | 2003-11-20 | — | — | WO | disclosed |