Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203544 | 0.83 | NPC1 (0.32) | TSHRNPC1RAB9AGAAMAPK1 | |
| SCHEMBL6203729 | 0.72 | NPC1 (0.33) | TSHRNPC1RAB9A | |
| SCHEMBL948252 | 0.70 | ALDH1A1 (0.46) | TSHRNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL12128652 | 0.68 | KDM4E (0.36) | RAB9AMAPK1ALDH1A1TDP1 | |
| SCHEMBL22883585 | 0.68 | KDM4E (0.36) | RAB9AMAPK1ALDH1A1TDP1 | |
| SCHEMBL25689244 | 0.68 | KDM4E (0.36) | RAB9AMAPK1ALDH1A1TDP1 | |
| SCHEMBL4398284 | 0.68 | KDM4E (0.33) | USP2ALDH1A1TDP1 | |
| SCHEMBL4262405 | 0.67 | ALDH1A1 (0.35) | SMN1; SMN2USP2ALDH1A1TDP1 | |
| SCHEMBL3364848 | 0.66 | KDM4E (0.37) | USP2ALDH1A1TDP1 | |
| SCHEMBL22883305 | 0.66 | TSHR (0.43) | TSHRRAB9AGAAMAPK1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501877-A1 | FLUORINATED POLYMERS | Honeywell International Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| US-20040126695-A1 | Fluorinated polymers | HONEYWELL INTERNATIONAL, INC. | 2004-07-01 | — | — | US | claimed |
| WO-2003095505-A1 | FLUORINATED POLYMERS | HONEYWELL INTERNATIONAL INC. (US) | 2003-11-20 | — | — | WO | claimed |
| EP-1501877-A1 | FLUORINATED POLYMERS | Honeywell International Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040126695-A1 | Fluorinated polymers | HONEYWELL INTERNATIONAL, INC. | 2004-07-01 | — | — | US | disclosed |
| WO-2003095505-A1 | FLUORINATED POLYMERS | HONEYWELL INTERNATIONAL INC. (US) | 2003-11-20 | — | — | WO | disclosed |