Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204096 | 0.77 | CES2 (0.39) | CES2CES1 | |
| SCHEMBL6769767 | 0.77 | CA1 (0.32) | CES2CES1 | |
| SCHEMBL6204937 | 0.74 | CES2 (0.38) | CES2CES1 | |
| SCHEMBL18242010 | 0.73 | CES2 (0.34) | CES2CES1 | |
| SCHEMBL6203796 | 0.73 | CES2 (0.32) | CES2CES1 | |
| SCHEMBL7123183 | 0.72 | CES2 (0.43) | CES2CES1 | |
| SCHEMBL2093713 | 0.72 | CES2 (0.37) | CES2CES1 | |
| SCHEMBL18242124 | 0.70 | CES2 (0.32) | CES2CES1 | |
| SCHEMBL22719437 | 0.69 | RAPGEF4 (0.31) | CES2CES1 | |
| SCHEMBL3686370 | 0.68 | MAPK1 (0.36) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |