Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619807 | 0.65 | TYMS (0.38) | CYP2C19HTT | |
| SCHEMBL6182717 | 0.62 | NPC1 (0.46) | KMT2A | |
| Dansylsarcosine SCHEMBL23850005 | 0.62 | CYP1A2 (0.50) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| Dansylsarcosine SCHEMBL30745135 | 0.62 | CYP1A2 (0.50) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL292554 | 0.60 | CA2 (0.51) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL8458814 | 0.60 | CYP1A2 (0.50) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL13274117 | 0.59 | CYP1A2 (0.71) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL27915735 | 0.59 | CYP1A2 (0.54) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL5650140 | 0.58 | KMT2A (0.77) | CYP1A2CYP2C19HIF1AKMT2AATM | |
| SCHEMBL31033068 | 0.58 | KMT2A (0.77) | CYP1A2CYP2C19HIF1AKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | claimed |