Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 7/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6226169 | 0.83 | KMT2A (0.56) | KMT2AALDH1A1LMNASMN1; SMN2CDK1 | |
| SCHEMBL6202355 | 0.80 | ALDH1A1 (0.46) | KMT2AALDH1A1LMNASMN1; SMN2CDK1 | |
| SCHEMBL6203983 | 0.76 | KMT2A (0.42) | KMT2AALDH1A1LMNASMN1; SMN2CDK1 | |
| SCHEMBL3445315 | 0.73 | CDK1 (0.49) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL6201910 | 0.73 | ALDH1A1 (0.49) | KMT2AALDH1A1LMNASMN1; SMN2CDK1 | |
| SCHEMBL6203399 | 0.72 | KMT2A (0.42) | KMT2AALDH1A1LMNASMN1; SMN2CDK2 | |
| SCHEMBL3445310 | 0.72 | CDK2 (0.49) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL3445903 | 0.71 | CDK2 (0.43) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL3445486 | 0.71 | CYP3A4 (0.54) | KMT2AALDH1A1SMN1; SMN2CDK1KDM4E | |
| SCHEMBL3444705 | 0.70 | CDK1 (0.64) | KMT2ACDK1CCNB2CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |