Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | UQCRB | P14927 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3149439 | 0.88 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1GAAATM | |
| SCHEMBL3162410 | 0.87 | LMNA (0.50) | ALDH1A1KMT2AMEN1KDM4EATM | |
| SCHEMBL3153829 | 0.85 | KDM4E (0.47) | ALDH1A1KMT2AMEN1KDM4EATM | |
| SCHEMBL2960166 | 0.85 | HSD17B10 (0.46) | HSD17B10UQCRBALDH1A1KMT2AMEN1 | |
| SCHEMBL8319058 | 0.85 | HSD17B10 (0.46) | HSD17B10UQCRBALDH1A1KMT2AMEN1 | |
| SCHEMBL3157948 | 0.82 | PSEN1 (0.36) | ALDH1A1KMT2AMEN1GAAATM | |
| SCHEMBL3163162 | 0.81 | POLB (0.42) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL3161831 | 0.80 | ACHE (0.49) | ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL3164298 | 0.79 | LMNA (0.41) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL3153129 | 0.79 | PSEN1 (0.41) | ALDH1A1KMT2AMEN1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585728-A1 | IMINO ACID DERIVATIVES FOR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES | Aventis Pharma Deutschland GmbH (DE) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004060874-A1 | IMINO ACID DERIVATIVES FOR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-07-22 | — | — | WO | disclosed |