Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551316 | 0.93 | LMNA (0.40) | AKR1C1NPC1RAB9ALMNAF2 | |
| SCHEMBL18790760 | 0.89 | CES2 (0.43) | NPC1RAB9ALMNAALDH1A1TSHR | |
| SCHEMBL28411324 | 0.83 | AKR1C1 (0.42) | AKR1C1LMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL9800616 | 0.82 | LMNA (0.38) | AKR1C1NPC1RAB9ALMNAF2 | |
| SCHEMBL4952380 | 0.81 | LMNA (0.35) | AKR1C1NPC1RAB9ALMNAF2 | |
| SCHEMBL18790793 | 0.81 | CES2 (0.46) | NPC1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL22872468 | 0.81 | CES2 (0.46) | NPC1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL9859980 | 0.79 | LMNA (0.39) | NPC1RAB9ALMNAF2ALDH1A1 | |
| SCHEMBL18790751 | 0.79 | TPMT (0.38) | CYP2C9 | |
| SCHEMBL5496475 | 0.79 | LMNA (0.43) | AKR1C1NPC1RAB9ALMNAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365318-B1 | BENZYL MONOKETALS AND USE THEREOF | MERCK PATENT GMBH (DE) | 2021-01-06 | — | — | EP | disclosed |
| WO-2017067634-A1 | BENZIL MONOKETALAND USE THEREOF | MERCK PATENT GMBH (DE) | 2017-04-27 | — | — | WO | disclosed |
| CN-103764708-B | Photopolymerizable composition, photopolymerizable coating agent, laminate, and polarizing plate | 东洋油墨SC控股株式会社 | 2016-12-14 | — | — | CN | disclosed |
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| US-6855710-B2 | Substituted indolines with an inhibitory effect on various kinases and complexes of CDKs | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-02-15 | — | — | US | disclosed |
| US-20040058978-A1 | Novel substituted indolines with an inhibitory effect on various kinases and complexes of CDKs | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-03-25 | — | — | US | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |
| EP-0221010-B1 | PHOTO-INITIATOR SYSTEMS FOR FREE-RADICAL POLYMERISATIONS | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | disclosed |
| EP-0146501-B1 | POLYMERIZABLE COMPOSITIONS | CIBA-GEIGY AG (CH) | 1988-03-16 | — | — | EP | disclosed |
| EP-0104143-B1 | PHOTOPOLYMERIZABLE COMPOSITIONS CONTAINING DIARYLIODOSYL SALTS | CIBA-GEIGY AG (CH) | 1986-10-29 | — | — | EP | disclosed |
| EP-0094914-B1 | PHOTOPOLYMERISATION WITH ORGANOMETAL SALTS | CIBA-GEIGY AG (CH) | 1986-09-24 | — | — | EP | disclosed |
| US-4593052-A | Polymerizable compositions containing diphenyliodosyl salts | CIBA-GEIGY CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0146501-A2 | Polymerizable compositions | CIBA-GEIGY AG (CH) | 1985-06-26 | — | — | EP | disclosed |
| US-4518676-A | Photopolymerizable compositions containing diaryliodosyl salts | CIBA GEIGY CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |
| EP-0104143-A1 | Photopolymerizable compositions containing diaryliodosyl salts | CIBA-GEIGY AG (CH) | 1984-03-28 | — | — | EP | disclosed |
| EP-0094914-A2 | Photopolymerisation with organometal salts | CIBA-GEIGY AG (CH) | 1983-11-23 | — | — | EP | disclosed |
| US-4190602-A | PHOTOCHEMICAL SENSITIZERS BY REACTION OF SULFUROUS ACID ESTER OR THIONYL CHLORIDE AND A PRIMARY ALCOHOL | CIBA-GEIGY CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058978-A1 | Novel substituted indolines with an inhibitory effect on various kinases and complexes of CDKs | CDK1, CDK2, CDK3 | AKR1C1 983/4885NPC1 4477/4885RAB9A 2092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.