Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551316 | 0.85 | LMNA (0.40) | LMNACA2CA4F2MAPT | |
| SCHEMBL6204352 | 0.82 | AKR1C1 (0.39) | LMNAF2HDAC4MAPTNPC1 | |
| SCHEMBL9859980 | 0.79 | LMNA (0.39) | LMNAF2MAPTNPC1MAPK1 | |
| SCHEMBL10817611 | 0.79 | ALDH1A1 (0.39) | LMNAMAPTNPC1MAPK1RAB9A | |
| SCHEMBL5496475 | 0.79 | LMNA (0.43) | LMNACA2CA4F2MAPT | |
| SCHEMBL7587882 | 0.78 | HDAC4 (0.40) | LMNACA2CA4F2HDAC4 | |
| SCHEMBL6896429 | 0.76 | LMNA (0.36) | LMNACA2CA4F2MAPT | |
| SCHEMBL11490512 | 0.76 | NPSR1 (0.37) | LMNAMAPTNPC1MAPK1RAB9A | |
| SCHEMBL18790793 | 0.75 | CES2 (0.46) | LMNAMAPTNPC1MAPK1RAB9A | |
| SCHEMBL22872468 | 0.75 | CES2 (0.46) | LMNAMAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269573-B1 | LIQUID PHOTOINITIATING MIXTURE | CIBA-GEIGY AG (CH) | 1991-03-27 | — | — | EP | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0221010-B1 | PHOTO-INITIATOR SYSTEMS FOR FREE-RADICAL POLYMERISATIONS | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | disclosed |
| EP-0269573-A2 | Liquid photoinitiating mixture | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | disclosed |
| EP-0100862-B1 | 2-ACYL-DIHYDRO-1,3-DIOXEPINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHOTOINITIATORS | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |
| EP-0221010-A1 | Photo-initiator systems for free-radical polymerisations | CIBA-GEIGY AG (CH) | 1987-05-06 | — | — | EP | disclosed |
| US-4485249-A | 2-Acylated dihydro-1,3-dioxepins, process for the production thereof and use thereof as photo-initiators | CIBA-GEIGY CORPORATION (US) | 1984-11-27 | — | — | US | disclosed |
| EP-0100862-A1 | 2-Acyl-dihydro-1,3-dioxepines, process for their preparation and their use as photoinitiators | CIBA-GEIGY AG (CH) | 1984-02-22 | — | — | EP | disclosed |