Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ABL2 | P42684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204423 | 1.00 | ALDH1A1 (0.40) | ALDH1A1GAALMNAHPGDKMT2A | |
| SCHEMBL21366179 | 0.85 | ALDH1A1 (0.44) | ALDH1A1GAALMNAHPGDKMT2A | |
| SCHEMBL5623918 | 0.84 | ALDH1A1 (0.41) | ALDH1A1GAALMNAHPGDKMT2A | |
| SCHEMBL5623910 | 0.84 | ALDH1A1 (0.41) | ALDH1A1GAALMNAHPGDKMT2A | |
| SCHEMBL14499189 | 0.84 | ALDH1A1 (0.47) | ALDH1A1GAALMNAHPGDKMT2A | |
| SCHEMBL74903 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GAALMNAHPGDKMT2A | |
| SCHEMBL74904 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GAALMNAHPGDKMT2A | |
| SCHEMBL26322204 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GAALMNAHPGDKMT2A | |
| SCHEMBL6207233 | 0.80 | ADH1A (0.45) | LMNAKMT2AADH1AKITFLT1 | |
| SCHEMBL18378477 | 0.79 | ALDH1A1 (0.42) | ALDH1A1GAALMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938474-B1 | CYCLOPROPYLINDOLE COMPOUNDS AND THEIR USE AS PRODRUGS | AUCKLAND UNISERVICES LTD (NZ) | 2005-11-23 | — | — | EP | disclosed |
| US-6130237-A | Condensed N-aclyindoles as antitumor agents | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-10-10 | — | — | US | disclosed |