Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ABL2 | P42684 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 3/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517373 | 0.89 | ADH1A (0.52) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6517367 | 0.89 | ADH1A (0.52) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL436370 | 0.89 | MMP13 (0.46) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6207384 | 0.87 | HDAC2 (0.44) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6206358 | 0.87 | HRH4 (0.46) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL8107297 | 0.86 | SMN1; SMN2 (0.45) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6206250 | 0.86 | MEN1 (0.44) | KDM4EKMT2AHRH4NPC1RAB9A | |
| SCHEMBL469094 | 0.85 | MMP13 (0.42) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL10111775 | 0.85 | MMP13 (0.42) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL16151965 | 0.84 | MMP13 (0.41) | ADH1AKITFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938474-B1 | CYCLOPROPYLINDOLE COMPOUNDS AND THEIR USE AS PRODRUGS | AUCKLAND UNISERVICES LTD (NZ) | 2005-11-23 | — | — | EP | disclosed |
| US-6130237-A | Condensed N-aclyindoles as antitumor agents | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-10-10 | — | — | US | disclosed |