Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | FFAR2 | O15552 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672924 | 0.81 | CHEK1 (0.43) | FFAR2CYP1A2LRRK2 | |
| SCHEMBL6155249 | 0.74 | LIMK1 (0.44) | LMNAADORA2AADORA1PI4KAPI4K2B | |
| Hydrochloric Acid SCHEMBL7166188 | 0.73 | PI4KA (0.45) | LMNAADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL10664748 | 0.70 | SMN1; SMN2 (0.42) | HTTSMN1; SMN2LMNAFFAR2ALOX15 | |
| SCHEMBL6322370 | 0.68 | DYRK1A (0.34) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21539447 | 0.66 | MTAP (0.39) | LMNAADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL14074704 | 0.66 | FFAR2 (0.33) | FFAR2 | |
| SCHEMBL9203283 | 0.65 | HTT (0.76) | HTTSMN1; SMN2LMNAMAP3K5ALDH1A1 | |
| SCHEMBL5019515 | 0.65 | HTT (0.41) | HTTSMN1; SMN2LMNAFFAR2ALOX15 | |
| SCHEMBL9124561 | 0.63 | SMN1; SMN2 (0.44) | HTTSMN1; SMN2LMNAFFAR2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551825-A1 | NOVEL DIRECT BLACK DYES WITH THREE HETEROAROMATIC RINGS | L'OREAL (FR) | 2005-07-13 | — | — | EP | disclosed |
| US-20050060815-A1 | Novel heteroaromatic trinuclear black direct dyes | L'OREAL S.A. (FR) | 2005-03-24 | — | — | US | disclosed |
| WO-2004031173-A1 | NOVEL DIRECT BLACK DYES WITH THREE HETEROAROMATIC RINGS | L'OREAL (FR) | 2004-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050060815-A1 | Novel heteroaromatic trinuclear black direct dyes | KRT18, MKI67, TUBA4A | HTT 845/4885SMN1; SMN2 4097/4885LMNA 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.