Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | SLC25A1 | P53007 | 2/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204952 | 1.00 | KMT2A (0.53) | KMT2AMEN1SLC25A1DNMT1DNMT3A | |
| SCHEMBL6205161 | 1.00 | KMT2A (0.53) | KMT2AMEN1SLC25A1DNMT1DNMT3A | |
| SCHEMBL6205259 | 0.87 | KMT2A (0.59) | KMT2AMEN1LMNAMAPTPOLB | |
| SCHEMBL6205252 | 0.87 | KMT2A (0.59) | KMT2AMEN1LMNAMAPTPOLB | |
| SCHEMBL6205255 | 0.87 | KMT2A (0.59) | KMT2AMEN1LMNAMAPTPOLB | |
| SCHEMBL24215474 | 0.86 | MEN1 (0.70) | KMT2AMEN1SLC25A1DNMT1DNMT3A | |
| SCHEMBL30515749 | 0.86 | MEN1 (0.70) | KMT2AMEN1SLC25A1DNMT1DNMT3A | |
| SCHEMBL6205955 | 0.84 | CASP3 (0.61) | KMT2ASLC25A1MAPTCASP3SENP8 | |
| SCHEMBL6205953 | 0.84 | CASP3 (0.61) | KMT2ASLC25A1MAPTCASP3SENP8 | |
| SCHEMBL6205956 | 0.84 | CASP3 (0.61) | KMT2ASLC25A1MAPTCASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |