Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205953 | 1.00 | CASP3 (0.61) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6205956 | 1.00 | CASP3 (0.61) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL8366106 | 0.85 | CASP3 (0.81) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6205161 | 0.84 | KMT2A (0.53) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6204952 | 0.84 | KMT2A (0.53) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6205157 | 0.84 | KMT2A (0.53) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6204555 | 0.82 | PGR (0.59) | KMT2APKMALDH1A1PGRKDM4E | |
| SCHEMBL6204561 | 0.82 | PGR (0.59) | KMT2APKMALDH1A1PGRKDM4E | |
| SCHEMBL6204559 | 0.82 | PGR (0.59) | KMT2APKMALDH1A1PGRKDM4E | |
| SCHEMBL6204568 | 0.81 | AKR1C3 (0.61) | KMT2APKMALDH1A1PGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |