Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204174 | 0.92 | HTR2A (0.35) | HTR2AHTR2CMEN1LMNAKMT2A | |
| SCHEMBL6203203 | 0.86 | CDK5 (0.40) | HTR2AHTR2CCDK5ATMCDK5R1 | |
| SCHEMBL6202086 | 0.86 | HTR2C (0.48) | HTR2AHTR2CMEN1LMNAKMT2A | |
| SCHEMBL6205216 | 0.86 | BRAF (0.36) | HTR2AHTR2CMEN1LMNAKMT2A | |
| SCHEMBL6205643 | 0.84 | CDK5 (0.45) | HTR2AHTR2CMEN1KMT2ACDK5 | |
| SCHEMBL6204146 | 0.82 | CCNE2 (0.45) | HTR2AHTR2C | |
| SCHEMBL6203247 | 0.81 | CCNE2 (0.43) | HTR2AHTR2CMEN1KMT2A | |
| SCHEMBL6204176 | 0.78 | BRAF (0.36) | HTR2AHTR2CMEN1LMNAKMT2A | |
| SCHEMBL3444318 | 0.75 | CDK5 (0.45) | CDK5CDK5R1 | |
| SCHEMBL6203167 | 0.74 | CCNE1 (0.41) | CDK5ATMCDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |