Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204146 | 0.89 | CCNE2 (0.45) | HTR2CHTR2AMAPTNPSR1CCNE2 | |
| SCHEMBL6203247 | 0.89 | CCNE2 (0.43) | HTR2CHTR2AMEN1KMT2ANPSR1 | |
| SCHEMBL6205643 | 0.88 | CDK5 (0.45) | HTR2CHTR2AMEN1KMT2AMAPT | |
| SCHEMBL6205210 | 0.86 | HTR2A (0.35) | HTR2CHTR2AMEN1KMT2ALMNA | |
| SCHEMBL6204174 | 0.86 | HTR2A (0.35) | HTR2CHTR2AMEN1KMT2ALMNA | |
| SCHEMBL6202094 | 0.84 | HTR2C (0.47) | HTR2CHTR2AMEN1KMT2AMAPT | |
| SCHEMBL6203203 | 0.83 | CDK5 (0.40) | HTR2CHTR2ACCNE2CCNE1CDK2 | |
| SCHEMBL6202754 | 0.76 | CDK5 (0.43) | MEN1KMT2ASMN1; SMN2CCNE2CCNE1 | |
| SCHEMBL6204126 | 0.76 | SLC29A1 (0.32) | — | |
| SCHEMBL6204714 | 0.74 | SLC29A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |