Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205057 | 0.98 | ALDH1A1 (0.37) | HTTALDH1A1GAAHPGDTP53 | |
| SCHEMBL6205391 | 0.98 | HTT (0.36) | HTTALDH1A1GAAHPGDTP53 | |
| SCHEMBL6204993 | 0.96 | HTT (0.36) | HTTALDH1A1GAAHPGDTP53 | |
| SCHEMBL1114602 | 0.78 | CYP3A4 (0.44) | HTTALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL6204538 | 0.72 | NOS3 (0.39) | HTTALDH1A1SMN1; SMN2PER2 | |
| SCHEMBL23907338 | 0.71 | NAAA (0.37) | HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL5638919 | 0.71 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4703842 | 0.70 | HSD17B10 (0.36) | ALDH1A1GAAPER2 | |
| SCHEMBL6045399 | 0.70 | HSD17B10 (0.33) | HTTALDH1A1 | |
| SCHEMBL6045233 | 0.70 | HSD17B10 (0.33) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534681-A1 | SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004002960-A1 | SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-01-08 | — | — | WO | disclosed |