Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.45 |
| ▸ | BRD1 | O95696 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | ATIC | P31939 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207659 | 1.00 | SLC22A12 (0.51) | SLC22A12HSP90AA1HSP90AB1KMT2AHSD17B1 | |
| SCHEMBL6207661 | 1.00 | SLC22A12 (0.51) | SLC22A12HSP90AA1HSP90AB1KMT2AHSD17B1 | |
| SCHEMBL6206539 | 0.84 | TSHR (0.57) | WDR5ITGA1FABP4FABP5 | |
| SCHEMBL6206726 | 0.84 | TSHR (0.57) | WDR5ITGA1FABP4FABP5 | |
| SCHEMBL6206728 | 0.84 | TSHR (0.57) | WDR5ITGA1FABP4FABP5 | |
| SCHEMBL6205304 | 0.80 | WDR5 (0.54) | KMT2AWDR5ITGA1FABP4FABP5 | |
| SCHEMBL6205307 | 0.80 | WDR5 (0.54) | KMT2AWDR5ITGA1FABP4FABP5 | |
| SCHEMBL6205309 | 0.80 | WDR5 (0.54) | KMT2AWDR5ITGA1FABP4FABP5 | |
| SCHEMBL6205383 | 0.78 | ITGA1 (0.53) | KMT2AWDR5ITGA1FABP4FABP5 | |
| SCHEMBL6205381 | 0.78 | ITGA1 (0.53) | KMT2AWDR5ITGA1FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |