Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.54 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205304 | 1.00 | WDR5 (0.54) | WDR5ITGA1PGRNPC1MEN1 | |
| SCHEMBL6205309 | 1.00 | WDR5 (0.54) | WDR5ITGA1PGRNPC1MEN1 | |
| SCHEMBL6205283 | 0.92 | WDR5 (0.58) | WDR5ITGA1NPC1MEN1KMT2A | |
| SCHEMBL6208434 | 0.92 | WDR5 (0.58) | WDR5ITGA1NPC1MEN1KMT2A | |
| SCHEMBL6208436 | 0.92 | WDR5 (0.58) | WDR5ITGA1NPC1MEN1KMT2A | |
| SCHEMBL6205543 | 0.89 | WDR5 (0.57) | WDR5ITGA1NPC1MEN1KMT2A | |
| SCHEMBL6206630 | 0.89 | WDR5 (0.57) | WDR5ITGA1NPC1MEN1KMT2A | |
| SCHEMBL6206627 | 0.89 | WDR5 (0.57) | WDR5ITGA1NPC1MEN1KMT2A | |
| SCHEMBL6205383 | 0.87 | ITGA1 (0.53) | WDR5ITGA1PGRNPC1MEN1 | |
| SCHEMBL6205102 | 0.87 | ITGA1 (0.53) | WDR5ITGA1PGRNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |